EXHIBIT 22.1

List of Subsidiary Issuers of Guaranteed Securities

As of December 31, 2023, COPT Defense Properties was the guarantor of the outstanding guaranteed debt securities of its subsidiaries, as listed below:

Debt Instrument Issuer
2.250% Senior Notes due 2026COPT Defense Properties, L.P.
2.000% Senior Notes due 2029COPT Defense Properties, L.P.
2.750% Senior Notes due 2031COPT Defense Properties, L.P.
2.900% Senior Notes due 2033COPT Defense Properties, L.P.